Azelaic acid + niacinamide, for dark spots and redness
For dark spots, marks left by breakouts, melasma and redness. Two well-known ingredients in one compounded cream, used across all skin tones.
For adults 18 and older located in Florida.
- Clinician care, follow-ups & free expedited shipping
- Medication included if prescribed
- Cancel anytime
- Full refund if not approved
Billing, cancellation & refund details
Includes your clinician review and follow-ups, strength adjustments, secure messaging open 7 days a week, free expedited shipping and, if your clinician determines it is appropriate, a 30 g prescription cream (about 2 months of use) prepared for you by a state-licensed pharmacy. Each 30 g cream lasts about 2 months with morning and evening use. It is compounded by a state-licensed 503A pharmacy.
Renews every 8 weeks at the same price until you cancel. Cancel anytime in your patient portal, at contact@nutreeclinic.com or at (305) 209-2066 before your next renewal date: no further charges and no cancellation fee. The current 8-week supply is non-refundable once a prescription is issued.
You pay now to reserve your program. A licensed clinician then reviews your intake. If treatment isn’t medically appropriate for you, you receive a full refund within 5 business days. Payment does not guarantee a prescription.
Who azelaic acid + niacinamide is for
- Dark spots
- Marks after acne
- Melasma
- Redness
It may be a good fit if
- You have dark spots, sun spots or marks left by breakouts
- You have melasma, or patches that darken in the sun
- Your skin flushes or looks red easily
Talk to your clinician first if
- You are pregnant, trying to conceive or breastfeeding
- You have very sensitive or broken skin on the area
- You use other lightening products, such as hydroquinone
- You notice lighter patches of skin after starting
Your clinician decides whether a prescription is appropriate for you, or recommends another option.
A simple routine, set by your clinician.
Morning and evening
Apply a thin layer to clean, dry skin over the whole area, not only the spots, as your clinician directs.
Expect a light tingle
A mild, temporary tingling or stinging is common in the first weeks. Tell your clinician if it does not settle.
Sunscreen every day
Sun is the main trigger for dark spots and melasma, so a broad-spectrum SPF 30 or higher every morning is part of the treatment.
Give it time
Pigment changes slowly. Many people need 12 weeks or more of regular use. Your clinician checks in and adjusts your plan.
Always follow your clinician’s instructions and the pharmacy label. Individual results vary.
Get started →Azelaic acid 15% / niacinamide 4%
Azelaic acid 15% / niacinamide 4% · 30 g
Two ingredients for uneven tone in one compounded cream: azelaic acid 15% and niacinamide 4%. Used across all skin tones. Possible side effects: Mild, temporary burning, stinging, tingling, itching or dryness. Rarely, lighter patches of skin: tell your clinician if you notice them.
How compounded medications work
Compounded medications are prescribed for an individual patient by a licensed clinician after a medical assessment, and prepared by a state-licensed 503A compounding pharmacy. They do not undergo FDA pre-market review or approval, and they may differ from FDA-approved drugs in effectiveness, safety and side effects. Results from clinical trials of FDA-approved medications should not be used to judge compounded medications.
Azelaic acid 20% cream is FDA-approved for mild to moderate acne and azelaic acid 15% gel or foam for rosacea; other uses are off-label. Azelaic acid 15% / niacinamide 4% cream is compounded by a state-licensed 503A pharmacy and is not FDA-approved.
For adults 18 and older located in Florida.
Important Safety Information
Prescription only. Treatment is prescribed only if a licensed provider determines it is medically appropriate after reviewing your health history. A prescription is never guaranteed.
Azelaic acid 15% / niacinamide 4% cream
Azelaic acid 20% cream is FDA-approved for mild to moderate acne, and azelaic acid 15% gel or foam for rosacea. Other uses are off-label.
Azelaic acid 15% / niacinamide 4% cream is compounded by a state-licensed 503A pharmacy. Compounded drugs are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality.
Do not use if
- You are allergic to azelaic acid, niacinamide, or any ingredient in the cream
- You have broken skin on the area to treat
Serious warnings and precautions
- Skin irritation: burning, stinging, or itching is usually mild and temporary. Stop and contact your provider if it is severe or does not settle.
- Rarely, lighter patches of skin have been reported, especially in darker skin tones. Tell your provider if you notice any.
- Avoid the eyes, mouth, and other mucous membranes. If it gets in your eyes, rinse with plenty of water.
- Asthma has been reported to get worse in some people using azelaic acid. Tell your provider if you have asthma.
Common side effects
Burning, stinging, tingling, itching, dryness, or redness where it is applied, mostly in the first weeks.
Pregnancy and breastfeeding
Tell your provider if you are pregnant, trying to conceive, or breastfeeding. They review whether this compounded cream is appropriate for you.
This is not a complete list of possible side effects or risks. Talk with your provider about the benefits and risks of any treatment, and tell them about all of your medical conditions and the medicines and supplements you take.
Nutree Clinic is not for medical emergencies. If you think you are having a medical emergency, call 911 or go to the nearest emergency room. If you are having thoughts of harming yourself, call or text 988.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
See Medication safety information for links to the FDA labels of the approved reference products.