Topical spironolactone, for breakouts that follow your cycle
For women with deep, recurring breakouts along the jaw, chin and neck. A compounded cream your clinician may prescribe, applied where you break out instead of taken as a pill.
For adults 18 and older located in Florida.
- Clinician care, follow-ups & free expedited shipping
- Medication included if prescribed
- Cancel anytime
- Full refund if not approved
Billing, cancellation & refund details
Includes your clinician review and follow-ups, strength adjustments, secure messaging open 7 days a week, free expedited shipping and, if your clinician determines it is appropriate, a 30 g prescription cream (about 2 months of use) prepared for you by a state-licensed pharmacy. Each 30 g cream lasts about 2 months with regular use. It is compounded by a state-licensed 503A pharmacy.
Renews every 8 weeks at the same price until you cancel. Cancel anytime in your patient portal, at contact@nutreeclinic.com or at (305) 209-2066 before your next renewal date: no further charges and no cancellation fee. The current 8-week supply is non-refundable once a prescription is issued.
You pay now to reserve your program. A licensed clinician then reviews your intake. If treatment isn’t medically appropriate for you, you receive a full refund within 5 business days. Payment does not guarantee a prescription.
Who topical spironolactone is for
- Hormonal acne
- Jawline & chin breakouts
- Breakouts with your cycle
It may be a good fit if
- You are a woman with breakouts along the jaw, chin or neck
- Your breakouts tend to flare around your period
- You prefer a cream to a daily pill
Talk to your clinician first if
- You are pregnant, trying to conceive or breastfeeding: spironolactone is not used
- You are a man: it is not recommended
- You have kidney problems, or take potassium supplements or blood pressure medicines
- You have very sensitive or broken skin on the area
Your clinician decides whether a prescription is appropriate for you, or recommends another option.
A simple routine, set by your clinician.
Apply a thin layer
Once or twice a day as your clinician directs, on clean, dry skin over the areas where you break out.
Pair it wisely
It can be used with other treatments, such as tretinoin, if your clinician recommends it. Keep the rest of your routine gentle.
Be consistent
Hormonal breakouts come and go with your cycle, so it takes regular use over several cycles to judge how it works for you.
Check in
Your clinician follows up and adjusts your plan. Message them anytime if your skin feels irritated.
Always follow your clinician’s instructions and the pharmacy label. Individual results vary.
Get started →Spironolactone 5% cream
Spironolactone 5% cream · 30 g
A compounded cream for breakouts along the jaw, chin and neck that tend to follow your cycle. Applied to the skin, instead of taken as a pill. Possible side effects: Dryness, redness or irritation where it is applied. Not for use during pregnancy or while trying to conceive. Tell your clinician about any changes in your cycle.
How compounded medications work
Compounded medications are prescribed for an individual patient by a licensed clinician after a medical assessment, and prepared by a state-licensed 503A compounding pharmacy. They do not undergo FDA pre-market review or approval, and they may differ from FDA-approved drugs in effectiveness, safety and side effects. Results from clinical trials of FDA-approved medications should not be used to judge compounded medications.
Spironolactone tablets are FDA-approved for conditions such as heart failure, high blood pressure and edema; use for acne is off-label. Topical spironolactone 5% is compounded by a state-licensed 503A pharmacy, is not FDA-approved, and evidence for topical use is limited.
For adults 18 and older located in Florida.
Important Safety Information
Prescription only. Treatment is prescribed only if a licensed provider determines it is medically appropriate after reviewing your health history. A prescription is never guaranteed.
Topical spironolactone 5% cream
Spironolactone tablets are FDA-approved for conditions such as heart failure, high blood pressure and edema; use for acne is off-label.
Topical spironolactone 5% is compounded by a state-licensed 503A pharmacy. Compounded drugs are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality. Evidence for topical use in acne is limited.
Do not use if
- You are pregnant, trying to conceive, or breastfeeding
- You are allergic to spironolactone or any ingredient in the cream
- You are male: spironolactone blocks male hormones and is not recommended
Serious warnings and precautions
- Skin irritation: stop and contact your provider if you have strong redness, burning, or a rash where you apply it.
- Some spironolactone can be absorbed through the skin. Tell your provider if you have kidney problems, high potassium, or Addison’s disease.
- Tell your provider about changes in your menstrual cycle or breast tenderness.
Common side effects
Dryness, redness, or irritation where it is applied.
Drug interactions
- Tell your provider if you take potassium supplements, salt substitutes, ACE inhibitors, ARBs, other diuretics, or NSAIDs on a regular basis.
Pregnancy and breastfeeding
Do not use during pregnancy or while trying to conceive: anti-androgens may affect the development of a male baby. Tell your provider if you are breastfeeding.
This is not a complete list of possible side effects or risks. Talk with your provider about the benefits and risks of any treatment, and tell them about all of your medical conditions and the medicines and supplements you take.
Nutree Clinic is not for medical emergencies. If you think you are having a medical emergency, call 911 or go to the nearest emergency room. If you are having thoughts of harming yourself, call or text 988.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
See Medication safety information for links to the FDA labels of the approved reference products.