Illustration of a compounded B12 + MIC injection vial
Illustration. Actual medication is labeled by the dispensing state-licensed 503A pharmacy.
Why B12 matters

B12 + MIC care, guided by licensed clinicians

B12 + MIC injections, prescribed if appropriate after provider review.

For adults 18 and older located in Florida.

B12 + MIC Care Program
Injectable · 1 month
If prescribed · one-time payment, no renewal
$119
for 1 month
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Injectable · 3 months
If prescribed · one-time payment, no renewal
$279
for 3 months
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  • Clinician care, follow-ups & free expedited shipping
  • Medication included if prescribed
  • One-time payment, no renewal
  • Full refund if not approved
Billing, cancellation & refund details

The B12 + MIC Care Program includes clinician review, dosing instructions, shipping and, if prescribed, a 1- or 3-month supply of B12 + MIC (vitamin B12 with methionine, inositol and choline) prepared by a state-licensed 503A compounding pharmacy.

One-time payment. Does not renew. Non-refundable once a prescription is issued.

You pay now to reserve your program. A licensed clinician then reviews your intake. If treatment isn’t medically appropriate for you, you receive a full refund within 5 business days. Payment does not guarantee a prescription.

See program terms → · Medication safety information

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FSA/HSA cards accepted · Free expedited shipping, if prescribed · One-time payment · no auto-renewal
Prescription only, if appropriate after provider review · Important Safety Information
B12 + MIC injectable, at the dose and schedule your clinician sets
Every fee is shown before you pay
Clinician review and dosing instructions included
If prescribed, your medication is shipped to your door, free
If prescribed, prepared by a state-licensed 503A compounding pharmacy
Secure, HIPAA-compliant messaging, open 7 days a week — no waiting rooms
100% online careFree expedited shippingFSA/HSA cards accepted7/7 secure messagingOne-time payment · no auto-renewalLegitScript certifiedLicensed 503A pharmacies100% online careFree expedited shippingFSA/HSA cards accepted7/7 secure messagingOne-time payment · no auto-renewalLegitScript certifiedLicensed 503A pharmacies
How it works

B12 + MIC injections, with your clinician setting the dose.

B12 + MIC injections deliver vitamin B12, with methionine, inositol and choline, without relying on digestion, which matters when absorption from food or pills is reduced. Your provider decides whether it is appropriate based on your health profile.

B12 + MIC injectable
Vitamin B12 with methionine, inositol and choline. Bypasses the digestive system — often used when absorption is reduced
Clinician-set dosing
A small injection at home, at the dose and schedule your clinician prescribes
Monitored
Your clinician reviews your response; noticeable changes in energy are more likely if you were low in B12
Why B12 matters

Why B12 matters

B vitamins help your body turn food into energy and support normal nerve function and red blood cell production. Your clinician reviews whether supplementation fits your symptoms, diet and labs.

B12 + MIC combines vitamin B12 with methionine, inositol and choline (MIC), nutrients often combined with vitamin B12 in compounded injections. Evidence for added benefit from MIC is limited.

Noticeable changes in energy are more likely if you are low in B12. Responses vary, and your clinician adjusts your plan over time.

Prescribed only if appropriate after a licensed provider review. Cyanocobalamin (vitamin B12) injection is FDA-approved for B12 deficiency; B12 + MIC is a compounded combination that is not FDA-approved. Use for energy or general wellness without a deficiency is off-label, and evidence for that use is limited. Images show models, not patients.

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The science

What B12 does in the body.

Energy metabolism at the cellular level
B12 is a cofactor in metabolic pathways the body uses to turn food into energy. Supplementing is most likely to help when levels are low.
Neurological function and mood
B12 is essential for healthy nerves and the protective myelin around them. Low B12 can affect mood, memory and nerve function.
Red blood cell formation
B12 is needed to produce healthy red blood cells. Low B12 can cause anemia, which can lead to tiredness and weakness.
What MIC adds
MIC stands for methionine, inositol and choline, nutrients often combined with vitamin B12 in compounded injections. Evidence for added benefit is limited, and the combination is not FDA-approved.
The form your clinician may prescribe

Compounded B12 + MIC injection

Illustration of a compounded B12 + MIC injection vial
Illustration. Actual medication is labeled by the dispensing state-licensed 503A pharmacy.

B12 + MIC injectable

Vitamin B12 with methionine, inositol and choline. A small injection at home, at the dose and schedule your clinician sets, if prescribed.

Other care areas

Other treatments patients discuss with their clinician

NAD+ Therapy
NAD+ Therapy
Energy and healthy-aging goals (off-label)
Sermorelin
Sermorelin
Sleep and recovery goals (off-label)
GLP-1 Weight Loss
GLP-1 Weight Loss
Clinician-guided weight care

Illustration. Actual medication is labeled by the dispensing state-licensed 503A pharmacy.

Frequently asked questions
About compounded medications

How compounded medications work

Compounded medications are prescribed for an individual patient by a licensed clinician after a medical assessment, and prepared by a state-licensed 503A compounding pharmacy. They do not undergo FDA pre-market review or approval, and they may differ from FDA-approved drugs in effectiveness, safety and side effects. Results from clinical trials of FDA-approved medications should not be used to judge compounded medications.

B12 + MIC (vitamin B12 with methionine, inositol and choline) prescribed through Nutree Clinic is compounded, and the combination is not FDA-approved. Cyanocobalamin injection is FDA-approved to treat vitamin B12 deficiency; use for energy or general wellness without a deficiency is off-label. Evidence for added benefit from MIC is limited.

For adults 18 and older located in Florida.

See program terms → · Medication safety information

Safety

Important Safety Information

Prescription only. Treatment is prescribed only if a licensed provider determines it is medically appropriate after reviewing your health history. A prescription is never guaranteed.

Compounded B12 + MIC injections

Cyanocobalamin (vitamin B12) injection is FDA-approved to treat vitamin B12 deficiency. Use for energy or general wellness in people without a deficiency is off-label, and evidence for that use is limited.

B12 + MIC prescribed through Nutree Clinic is compounded by a state-licensed 503A compounding pharmacy. It contains vitamin B12 (cyanocobalamin) with methionine, inositol and choline (MIC). Compounded medications, including the B12 + MIC combination, are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality. Evidence for added benefit from MIC is limited.

Do not use if

  • You are allergic to vitamin B12, cobalt, methionine, inositol, choline, or any other ingredient in the injection. Tell your provider about any allergies before starting
  • You have early Leber’s hereditary optic neuropathy (Leber’s disease) — B12 has been associated with rapid optic nerve damage in this condition

Serious warnings and precautions

  • Rare but serious allergic reactions, including anaphylaxis, have been reported. Get emergency help for swelling, trouble breathing, or a severe rash.
  • Low potassium can occur in the first days of treating severe B12-deficiency anemia; your provider may check your levels.
  • B12 can hide the signs of folate deficiency, and may unmask a condition called polycythemia vera.

Common side effects

Pain or redness at the injection site, mild diarrhea, itching, rash, and a feeling of swelling.

Pregnancy and breastfeeding

Tell your provider if you are pregnant or breastfeeding before starting injections.

This is not a complete list of possible side effects or risks. Talk with your provider about the benefits and risks of any treatment, and tell them about all of your medical conditions and the medicines and supplements you take.

Nutree Clinic is not for medical emergencies. If you think you are having a medical emergency, call 911 or go to the nearest emergency room. If you are having thoughts of harming yourself, call or text 988.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

See Medication safety information for links to the FDA labels of the approved reference products.

B12 + MIC (vitamin B12 with methionine, inositol and choline) prescribed through Nutree Clinic is compounded by state-licensed 503A compounding pharmacies. Compounded preparations, including the B12 + MIC combination, are not FDA-approved, and the FDA does not review compounded drugs for safety, effectiveness, or quality. Cyanocobalamin (vitamin B12) injection is FDA-approved for B12 deficiency; use for energy or general wellness without a deficiency is off-label. Evidence for added benefit from MIC is limited. Prescriptions are issued only if a licensed provider determines treatment is appropriate. Individual results vary. Care is available to patients located in Florida. Nutree Clinic LLC · Florida · LegitScript certified.
Ready to take the next step?
A licensed provider reviews your intake; a video or phone visit may be required depending on your treatment and Florida rules. Treatment is prescribed only if appropriate.
·If you start care within 30 days, your $15 consultation fee comes off your first program fee (or the $120 initial consultation for brand-name care). It can’t be used toward brand-name medication bought at your pharmacy. Secure messaging, open 7 days a week.
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