At Nutree Clinic, we believe that true success in weight management isn’t just measured in pounds lost — it’s measured in how well you sustain those results and how strong, balanced, and healthy you feel along the way.

Whether your plan includes a brand-name medication like Semaglutide (Wegovy®, Ozempic®) or Tirzepatide (Mounjaro®, Zepbound®), or a  Pharmacy Compounded formulation prescribed through our trusted pharmacy partners, your diet plays a defining role in your transformation.

Medications can help reset appetite and metabolism — but what determines the quality of your weight loss is how you fuel, nourish, and protect your body while on treatment.

Why Your Diet Matters So Much on GLP-1 and GIP/GLP-1 Treatments

GLP-1 medications work by mimicking natural gut hormones that regulate hunger and blood sugar. As appetite decreases, it becomes easier to eat less — but also easier to under-eat the nutrients your body still needs.

Clinical research published in The Lancet Diabetes & Endocrinology (2024) found that up to 30–40% of total weight lost through these therapies may come from lean body mass (e.g., muscle) when diet and physical activity aren’t optimized. That kind of loss can reduce metabolism, energy, and long-term sustainability.

At Nutree Clinic, our goal is not just weight loss — it’s metabolic health, muscle preservation, and vitality.

Understanding the Medications — and Why Nutrition Must Adapt

GLP-1 Receptor Agonists

Examples: Semaglutide (Wegovy®, Ozempic®), Liraglutide (Saxenda®)
These medications mimic a gut hormone (GLP-1) that increases satiety and slows digestion. The result: smaller portions, fewer cravings, and smoother blood-sugar control.

However, with less overall food intake, maintaining muscle and micronutrient balance becomes essential.

GIP/GLP-1 Dual Agonists

Example: Tirzepatide (Mounjaro®, Zepbound®)
This next-generation option activates both GLP-1 and GIP receptors, improving glucose metabolism and fat loss even further. Studies show it may help preserve lean mass slightly better than GLP-1 alone — but only when paired with a protein-rich diet and consistent movement.

Compounded GLP-1 Medications

Nutree Clinic partners exclusively with licensed 503A compounding pharmacies that meet the highest U.S. safety, sterility, and quality standards.

We select our partners for their validated testing, FDA apporoved pharmaceutical-grade ingredients, and dosing precision, ensuring that every formulation meets our medical standards for safety and efficacy.

Each prescription is supported by continuous follow-up, nutrition guidance, and clinical monitoring — because medication alone is never the full solution.

The Core Principles of Eating Well on Weight-Loss Medications

1. Prioritize Lean Protein

Protein is your body’s best defense against muscle loss. It maintains metabolic rate, supports recovery, and helps keep you fuller longer — a key advantage when appetite is low.

Goal: 1.2–1.5 g of protein per kg of body weight daily (≈ 80–100 g for most adults)
Sources: lean meats, fish, eggs, Greek yogurt, tofu, legumes, or protein shakes
Timing: spread protein evenly throughout meals to optimize absorption and satiety

At Nutree Clinic, our nutrition specialists design balanced meal plans that make hitting your protein goals effortless — even for patients with reduced appetite.

Examples:

• ½ chicken breast (≈ 26 g protein / 130 cal)

• ¾ cup non-fat Greek yogurt (≈ 17 g protein / 90 cal)

💡 Want the full chart with 20 protein sources, serving sizes, and calories?
📊 Scroll down to request your personalized Protein & Portion Guide.

2. Choose Whole, Nutrient-Dense Foods

A Mediterranean-inspired eating pattern — rich in vegetables, fiber, healthy fats, and lean proteins — complements GLP-1 and GIP/GLP-1 medications beautifully. It supports heart health, gut balance, and satiety without deprivation.

Key foods:

• Leafy greens and vegetables (spinach, zucchini, green beans, brocoli, carrots, squash...)

• Whole grains like quinoa, farro, and oats

• heathy fats such as Olive oil, nuts, and seeds for hormone support

• Legumes for additional fiber and plant protein

3. Don’t Over-Restrict Calories

Appetite suppression can make it easy to under-fuel, which may slow metabolism or cause fatigue.

• Avoid diets below 1,000 cal/day unless prescribed

• Stay tuned to your body’s energy levels

• Drink water throughout the day

• Remember: consistent nourishment leads to better results than extreme restriction.

Your Nutree Clinic provider will help adjust both medication dosing and nutrition to keep your progress safe and sustainable.

4. Protect Micronutrients and Hydration

Lower food intake means you must be intentional about vitamins and minerals.

Pay attention to:

• Calcium & Vitamin D — for bone and muscle support

• Magnesium, B12, Iron — for energy and metabolism

• Electrolytes & hydration — especially if experiencing slower digestion

Your Nutree Clinic provider may recommend targeted supplementation and periodic lab testing to ensure optimal nutrient balance.

A Balanced Day of Meals

Common Challenges — and How Nutree Clinic Helps

The Nutree Clinic Difference

At Nutree Clinic, we don’t believe in shortcuts.
We believe in guided care for real change — combining medical science, personalized nutrition, and trusted compounded formulations.

Every patient receives:

• Clinician-supervised treatment based on lab health goals

• Access to certified compounding pharmacies with pharmaceutical-grade standards

• A customized nutrition framework to protect muscle and metabolism

• Ongoing follow-up — because sustainable progress requires continuous care

Deeply personal care. Real medical results. True well-being.

🩺 Get Your Personalized Protein & Portion Guide

Want to know exactly how much protein you should eat — and which foods give you the best results while on GLP-1 or Tirzepatide?

We’ve created a free, clinician-designed Protein & Portion Chart that shows:
✅ The top-rated foods for weight loss with medication
✅ Protein grams and calories per serving
✅ How to balance your plate for fat loss without losing musclex

📩 Request your guide here

Ready to Begin Your Journey?

Book your consultation with a Nutree Clinic provider today.
We’ll review your health, labs, and lifestyle to design a treatment + nutrition plan that’s safe, personal, and built to last — including the highest-quality compounded medications and continuous clinical support.

Because when medical care feels personal, transformation lasts.

References

• The Lancet Diabetes & Endocrinology, “Muscle Matters: The Effects of Medically Induced Weight Loss on Skeletal Muscle” (2024)

• Mass General Advances in Endocrinology, “Preserving Lean Body Mass in Patients Taking GLP-1 for Weight Loss” (2024)

• Verywell Health, “Anti-Obesity Medication Nutrition Guidance” (2024)

• UNC Wellness, “Optimizing Nutrition While Taking GLP-1 Medications” (2025)

• The Fast 800, “What to Eat While Using Weight-Loss Medications” (2024)